Treatments We Offer

 

Spravato (Esketamine)

Spravato is an FDA-approved nasal spray for treatment-resistant depression (and for certain patients with depression and acute suicidal ideation/behavior when used with an oral antidepressant). Treatment is delivered in a structured clinical setting with required monitoring after dosing.

 

You may be a fit if you:

• Have depression that hasn’t improved with standard treatments

• Need a structured, clinic-based protocol with monitoring

• Want an evidence-based option with FDA approval

 

What to expect

• Eligibility review and treatment planning

• Scheduled dosing visits with observation afterward

• Ongoing symptom tracking and medication management

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Oral Ketamine (At-Home Protocols May Be Considered)

Oral ketamine is sometimes used off-label in psychiatry. When appropriate, it can be part of a carefully supervised plan that includes dosing guidance, symptom monitoring, and follow-up visits.

 

Oral ketamine may be considered when:

• You need flexibility and a structured outpatient plan

• You can follow safety instructions and monitoring requirements

• Your clinician determines the risk/benefit profile fits your needs

 

Off-label use means a medication is used in a way not specifically listed in FDA labeling. Your clinician will explain rationale, alternatives, and safety considerations.

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Conditions We Commonly Evaluate for Ketamine-Based Treatment

We assess ketamine options for patients who may be dealing with:

• Depression (including treatment-resistant depression)

• PTSD symptoms

• Anxiety symptoms

• Severe mood symptoms with functional impairment

 

Please note that this page is entirely informational—final eligibility depends on a clinical evaluation, history, and safety screening.

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How Ketamine Care Works at Pine Ridge

 

1) Consultation & Medical Screening

We review your symptoms, treatment history, medications, and relevant medical/psychiatric factors to determine if ketamine-based care is appropriate.

 

2) Personalized Plan

If you qualify, we’ll recommend the most appropriate pathway:

• Spravato (esketamine) protocol, or

• Oral ketamine plan (when clinically appropriate)

 

3) Treatment + Monitoring

Your plan includes:

• Symptom tracking and structured follow-ups

• Dose adjustments when needed

• Coordination with your broader mental health plan

 

4) Ongoing Support

Ketamine is not “one-and-done.” We focus on sustainable improvement with ongoing reassessment and continuity of care.